Welcome to the Brodsky Lab
We are a Research Group at the University of Pennsylvania located on the Third floor of the Rosenthal Building at the School of Veterinary Medicine. We take a variety of biochemical, genetic, cell biology, and systems-based approaches to address fundamental questions at the host-pathogen interface.
In particular we are interested in innate immune defense against enteric bacterial pathogens. We study Pattern Recognition and inflammatory cell death signaling in response to the gram-negative bacteria Salmonella and Yersinia, and how interactions between these innate immune responses and bacterial virulence strategies influence the outcome of infection.