Welcome to the Brodsky Lab
The Brodsky Lab at the University of Pennsylvania is located on the Third floor of the Rosenthal Building at the School of Veterinary Medicine. We take a variety of biochemical, genetic, cell biology, and systems-based approaches to investigate host-pathogen interactions. In particular we are interested in innate immune defense against enteric bacterial pathogens. We study pattern recognition receptor and inflammatory cell death signaling in response to the gram-negative bacteria Salmonella and Yersinia, and how interactions between these innate immune responses and bacterial virulence factors influence the outcome of infection.